The potential impact of an HIV vaccine with limited protection on HIV incidence in Thailand: A modeling study

The following is an abstract about the potential benefits of a HIV vaccine. It mentions 'risk compensation' which means abandoning condoms. It points out that mathmatical modelling shows that a partially effective vaccine may lead to increased HIV among sex workers if sex workers are less able to persuade clients to use condoms. The same is true of Prep and microbicides.

The potential impact of a moderately effective HIV vaccine with rapidly waning protection in South Africa and Thailand

Although published data from the recent ALVAC/AIDSVAX trial in Thailand (RV144) indicated the HIV vaccine provided very modest protection overall (31.2%), new analysis of trial data has suggested higher efficacy levels earlier in the follow-up period. CDC and UNAIDS organized several modeling research teams to explore the implications of the trial results and potential utility of this vaccine.

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